Welcome
Welcome to the International Meeting
HORIZONS IN NEUROSCIENCE - ORGANOIDS, OPTOGENETICS AND REMOTE CONTROL
organized by the Study Group “Molecular Neurobiology” as part of the German Society for Biochemistry and Molecular Biology (GBM) and the RUB Research School. With this Meeting, we bring together a wide range of Neuroscientists from Germany, Austria, Denmark, Sweden, Italy, Great Britain, Japan and the USA to explore new perspectives of understanding brain functions and the non-invasive methods of their modulation. In 3 plenary lectures we discuss therapeutic transplantation of stem cell-derived neurons in Parkinson`s disease, the quality control of protein folding in cells and the development of new optogenetic tools in neuronal networks in vivo. In 6 symposia we will bridge a broad field of approaches including induced stem cell technology (iPS), 3D cell culture to investigate brain functions and transplantation, magnetic guidance of neurite growth by functionalized iron core nanoparticles, the epigenetic control of protein expression, the investigation of synaptic connectivity by in vivo super resolution STED microscopy and analysis of memory function in neurodegenerative diseases. In addition, there will be lunch sessions on research in the bioscience industry, spectroscopic methods and biomarkers. We would also like to draw your attention to the young scientists that will present their work in poster or oral presentations. This is a great opportunity to meet the upcoming new generation of promising young researchers and students can meet the “PI”. Within the sessions we will have presentations selected from the abstracts. The poster sessions, scheduled on Wednesday, Thursday and Friday offer dynamic, vivid and personal presentations allowing to forge new collaborations and to discover new fields and ideas. Finally, we wish to draw your attention to the industry exhibitions. Major companies from the fields of modern spectroscopy and bioscience will present their products and services. We thank all our sponsors, whose contributions have greatly helped in shaping this event.
We wish all participants, speakers and presenters an enjoyable and productive conference!
Program
Registration and Welcome (11:00 - 13:50)
| 11:00 - 13:30 | Registration and Poster Mounting |
| 13.30 - 13:50 | Welcome Notes by the Dean of the Faculty of Chemistry and Biochemistry and the Conference Chair |
Research School Symposium, Plenary Lecture and Poster Session 1 (13:50 - 21:00)
| Research School Symposium chaired by Tim Ziebarth, Annika Haak, Lisa Bachmann, Lucia Gallego and David Marks | |
| 13:50 - 14:10 | Welcome and Introduction |
| 14:10 - 14:40 |
Ilaria Testa, Stockholm, SE (virtual) 4D nanoscopy of neuronal cells |
| 14:40 - 15:10 |
Brian J Bacskai, Boston, USA Optical imaging of pathophysiology in mouse models of Alzheimer's disease |
| 15:10 - 15:40 | Coffee Break |
| 15:40 - 16:10 |
Giorgia Quadrato, LA, USA (virtual) Upgrading the physiological relevance of human brain organoids |
| 16:10 - 16:40 |
Daniela Petrobon, Padova, IT Insights into migraine mechanisms from genetic mouse models of the disease |
| 16:40 - 17:00 |
Short Break |
| Plenary Lecture chaired by Andreas Reiner |
|
| 17:00 - 18:00 |
Stefan Herlitze, Bochum, DE Optogenetic control and visualization of GPCR pathways, or a journey from mouse brain to bioluminescent fish |
| Poster Session organized by RUB Research School |
|
| 18:00 - 21:00 |
Poster Session 1 Get Together with Food |
Session 1, Plenary Lecture, Networking (08:50 - 14:00)
| Session 1 - Remote Control of Neurite Growth - chaired by Rolf Heumann and David Marks |
|
| 08:50 - 09:00 | Opening of Session 1 |
| 09:00 - 09:30 |
Victoria Raffa, Pisa, IT Force as messenger of axon outgrowth and neural maturation: novel insights based on magnetic nano-pulling |
| 09:30 - 09:50 |
Peter Blümler, Mainz, DE Magnetic Guiding with Permanent Magnets |
| 09:50 - 10:20 | Coffee break |
| 10:20 - 10:40 |
Fabian Raudzus, Kyoto, JP Magnetic spatiotemporal control of SOS1 coupled nanoparticles for guided neurite growth |
| 10:40 - 10:50 | Tsvetan Serchov, Strasbourg, FR The role of the molecular circadian clock in the neurobiology and rapid treatment of depression |
| Plenary Lecture chaired by Rolf Heumann |
|
| 11:00 - 12:00 |
Jun Takahashi, Kyoto, JP (virtual) iPS cell-based therapy for Parkinson's disease |
| 12:00 - 13:00 | Lunch Break |
| 12:30 - 12:50 | Company Presentation |
| Networking |
|
| 13:00 - 14:00 | Business Meeting for Study Group Members |
| 13:00 - 14:00 | Meet-the-PI (RUB Research School) |
Sessions 2 and 3, Poster Session and Social Program (14:00 - open end)
| Session 2 - Organoids and Gene Editing - chaired by Thorsten Müller and Lucia Gallego |
|
| 14:00 - 14:30 |
Alessandro Prigione, Düsseldorf, DE Region-specific brain organoids for modeling and drug discovery of mitochondrial diseases |
| 14:30 - 14:40 | Sarah Hoerner, Mannheim, DE Human iPSC and 3D-Bioprinting Technologies for the Development of Neuromuscular Tricultures Including Glia Cells |
| 14:40 - 15:00 | Christopher Esk, Wien, AT Systematic analysis of human brain tissue development using cerebral organoids |
| 15:00 - 15:20 | Dominik Paquet, Munich, DE Human iPSC-derived 3D tissue models to investigate neurodegenerative and neurovascular diseases. |
| 15:20 - 15:40 | Jay Gopalakrishnan, Düsseldorf, DE Forebrain organoids innately developing bilateral optic vesicles |
| Poster Session 2 | |
| 15:40 - 17:00 |
Poster Session 2 Coffee Break |
| Session 3 - Optogenetics: New Actuators, Sensors and Applications - chaired by Andreas Reiner and Tim Ziebarth |
|
| 17:00 - 17:10 | Opening of Session 3 |
| 17:10 - 17:40 | Simon Wiegert, Hamburg, DE New tools for controlling neurons with light: Tweaking the nuts and bolts of the optogenetics toolbox |
| 17:40 - 18:05 | Olivia Masseck, Bremen, DE sDarken: A new family of genetically encoded serotonin sensors |
|
18:05 - 18:30 |
Benjamin Rost, Berlin, DE Optogenetic Manipulations of the Presynapse |
| Session 4.1 - Functional and Nanoscale Imaging in Health and Neurodegenerative Disease - chaired by Tim Hucho, Andreas Reiner and Annika Haak |
|
| 18:30 - 18:40 | Opening of Session 4.1 |
| 18:40 - 18:50 | Thomas Enzlein, Mannheim, DE Computational Analysis of Alzheimer Amyloid Plaque Composition in 2D- and Elastically Reconstructed 3D-MALDI MS Images |
| 18:50 - 19:00 | Annika Guntermann, Bochum, DE Looks like a starry sky - autoantibody screening in traumatic spinal cord injury |
| 19:00 - 19:10 | Simon Ebbinghaus, Braunschweig, DE The role of CAG triplet repeat RNA unfolding in cellular localization and condensate association with possible implications for Huntington's disease |
| Get-Together |
|
| 19:30 - open end |
Informal get-together at Q-West (located at the university campus) |
Plenary Lecture and Session 4 (08:50 - 12:55)
| Plenary lecture chaired by Thomas Günther-Pomorski |
|
| 09:00 - 10:00 |
Konstanze Winklhofer, Bochum, DE Shaping the ubiquitin coat of protein aggregates: A role of LUBAC in protein quality control |
| Session 4.2 - Functional and Nanoscale Imaging in Health and Neurodegenerative Disease - chaired by Tim Hucho, Andreas Reiner and Annika Haak | |
| 10:00 - 10:10 | Opening of Session 4.2 |
| 10:10 - 10:40 |
Oliver Bruns, Munich, DE Biomedical Imaging beyond the Visible - Fluorescence Imaging in the Shortwave-Infrared |
| 10:40 - 11:00 |
Cordelia Imig, Copenhagen, DK Caught in the Act: Ultrastructural Imaging of Synaptic Vesicle Pools |
| 11:00 - 11:30 | Coffee Break |
|
11:30 - 11:40 |
Sebastian Timmler, Cambridge, UK Region-specific myelin changes along the mouse lifespan |
| 11:40 - 11:50 | Annika Haak, Bochum, DE Investigation of Oligodendrocyte Progenitor Cell Tips with Scanning Ion Conductance and Expansion Microscopy |
| 11:50 - 12:10 | Katrin Willig, Göttingen, DE Multi-color in vivo STED microscopy of the synaptic nanoarchitecture and its activity-dependent nanoplasticity |
| 12:10 - 13:10 | Lunch Break |
Session 5, Poster Session 3, Awards & Prizes and Plenary Lecture (12:55 - 17:00)
|
Session 5 - Disease Models - chaired by Volkmar Lessmann, Jörg Bartsch and Lisa Bachmann |
|
| 13:10 - 13:20 | Opening of Session 5 |
| 13:20 - 13:50 | Albrecht Stroh, Mainz, DE Targeting early neuronal network dysregulations across brain disorders: Towards early network state-informed interventions |
| 13:50 - 14:00 | Sebastian Neumann, Bochum, DE Is H-Ras induced neuronal protection mediated by the plasmalemmal voltage-dependent anion channel-1 (pl-VDAC-1)? |
| 14:00 - 14:30 | Silvia Capello, Munich, DE (virtual) Extracellular Signaling in Neurodevelopmental Disorders |
|
Lunch Break & Meet-the-PI (RUB Research School) Coffee Break & Poster Session |
|
| 14:30 - 15:00 |
Lunch Break Meet-the-PI organized by RUB Research School |
| 15:00 - 15:30 | Poster Session 3 Coffee Break |
| Awards |
|
| 15:30 - 15:40 | Poster prize |
| 15:40 - 15:50 | Young scientist award |
|
Closing - Lecture organised by the JGBM students chaired by Marie Ziegler and Annika Haak |
|
| 15:50 - 16:00 | Welcome and Introduction |
| 16:00 - 16:30 | Edward Boyden, MIT, USA (virtual) Tools for Analyzing and Repairing the Brain |
| 16:30 - 16:45 | Closing remarks |
Registration
Deadlines:
early bird - 08.08.2022
abstract submission - 14.09.2022
Conference Fees and Registration Links:
invited speaker:
click here to register as an invited speaker!
member of the organizing team:
click here to register as a member of the organizing team!
student: 25,00 €
click here to register as a student!
retiree: 60,00 €
click here to register as a retiree!
regular participant: 75,00 €
click here to register as a regular participant!
reduced early bird fee (only until 08.08.2022): 60,00 €
Abstract Submission
Please use the following link to submit your abstract:
Please submit your abstract via the registration tool after your registration for the conference.
By mid September, you will receive information whether your abstract has been accepted for a short talk or poster presentation.
Please prepare poster contributions on DIN A0 (approx. 1200x840 mm), portrait format.
Please refer to the program for the poster session and abstract talk times.
Organization & Contact
Organizer:
Prof Dr. Günther-Pomorski
Chair:
Rolf Heumann
Scientific Organizing Team:
PhD-Students: Tim Ziebarth, Annika Haak, Lucía Gallego Villarejo, David Marks, Lisa Bachmann
PIs: Jörg Bartsch, Rolf Heumann (Chair), Tim Hucho, Volkmar Leßmann, Thorsten Müller, Andreas Reiner
jGBM: Maite Brachthäuser, Max Halupczok, Linda Siegert, Marie Ziegler
Contact:
rolf.heumann@ruhr-uni-bochum.de
This conference was supported by the Ruhr University Research School, funded by Germany’s Excellence Initiative [DFG GSC 98/3].
